In 1928 Hsueh and Marvel2 prepared the d and 1 5, 5-~-octylethylbarbituric acid, and reported that the d, 1 and dl forms had practically the same physiologic effect. Since the s- octylethylbarbituric acids required such a large dose to produce any effect they were not as ideally suited for study as certain other barbituric derivatives. In 1932 Sobotka and co- workers4 prepared d and 1 phenylethylhydantoin. In this series of comp0und. s the ...
