Ring??Closing Metathesis in the Synthesis of BC Ring??Systems of Taxol

…, S Schiltz, XF Le Goff, J Prunet

文献索引：Ma, Cong; Schiltz, Stephanie; Le Goff, Xavier F.; Prunet, Joelle Chemistry - A European Journal, 2008 , vol. 14, # 24 p. 7314 - 7323

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被引用次数: 27

摘要

Abstract BC ring-systems of taxol with different or no protecting group for the C1, C2-diol moiety have been efficiently synthesized. The eight-membered B ring is formed by a ring- closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. The influence of the 1, 2-diol protecting group on the RCM reaction has been studied in detail.