A new α-amono acid synthesis via an acetimidate rearrangement

S Takano, M Akiyama, K Ogasawara

文献索引：Takano, Seiichi; Akiyama, Masashi; Ogasawara, Kunio Journal of the Chemical Society, Chemical Communications, 1984 , # 12 p. 770 - 771

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被引用次数: 10

摘要

A new efficient synthesis of a-amino acids from ally1 alcohol derivatives via an acetimidate rearrangement has been deve I o ped . ... Although a wide range of methods is available for the synthesis of a-amino acids,' there are very few examples employing the cleavage of an alkene for the construction of the carboxy moiety2 probably because of the reactivity of the amine moiety under the oxidative conditions used. We describe herein a new synthesis of a-amino acids using just such a ...