Metal-and ligand-free Ullmann-type C–O and C–N coupling reactions promoted by potassium tert-butoxide

…, C Wu, M Ruan, Y Yang, Y Zhao, J Niu, W Yang, J Xu

文献索引：Yang, Shuliang; Wu, Cunqi; Ruan, Mingbo; Yang, Yanqin; Zhao, Yongxia; Niu, Jiajia; Yang, Wei; Xu, Jingwei Tetrahedron Letters, 2012 , vol. 53, # 33 p. 4288 - 4292

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被引用次数: 15

摘要

A simple, metal-and ligand-free procedure for the Ullmann-type C–O coupling reactions has been achieved by allowing aryl bromides to react with a variety of phenols in the presence of t-BuOK. Moderate to excellent yields of O-arylation products are obtained under mild conditions in a short time. In addition, two examples of C–N coupling reactions are also reported. A benzyne mechanism is proposed according to the experiment data.