Structure–activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: Carboxamide modification

X Sun, J Qiu, SA Strong, LS Green, JWF Wasley…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 6 p. 2338 - 2342

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被引用次数: 6

摘要

... Bioorganic & Medicinal Chemistry Letters. ... of the pyrrole based GSNOR inhibitors related to N6022 including the identification of pyrrole regioisomer 17 25 and potent GSNOR inhibitor 8f 26 with reduced CYP inhibition, as shown in Figure 2. In this Letter, we discuss the ...