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Structure-Affinity Relationships of a Unique Nicotinic Ligand: N 1-Dimethyl-N4-phenylpiperazinium Iodide (DMPP)

MN Romanelli, D Manetti, S Scapecchi…

文献索引:Journal of Medicinal Chemistry, , vol. 44, # 23 p. 3946 - 3955

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被引用次数: 43

摘要

... Journal of Medicinal Chemistry. ... Since the structure of the receptor has not been resolved at the atomic level, medicinal chemists have relied on classical structure−activity relationships of the ligands to elucidate the binding site of nicotinic drugs. ...