Journal of fluorine chemistry

α-or β-trifluoromethyl epoxysulfones: New C 3 reagents for heterocyclisation

F Laduron, Z Janousek, HG Viehe

文献索引：Laduron, Frederic; Janousek, Zdenek; Viehe, Heinz, G. Journal of Fluorine Chemistry, 1995 , vol. 73, # 1 p. 83 - 86

全文：HTML全文

被引用次数: 19

摘要

The syntheses of α-and β-trifluoromethyl epoxysulfones 1 and 2 are described. Compound 1 reacts with nucleophiles and bis-nucleophiles to furnish trifluoromethyl ketones and trifluoromethyl heterocycles in good yield, while its isomer 2 leads to the opposite thiazole regioisomers with thioamides.