Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases

…, M Pocci, F Lucchesini, A De Munno

文献索引：Bertini, Vincenzo; Lucchesini, Francesco; Pocci, Marco; Munno, Angela De Heterocycles, 1995 , vol. 41, # 4 p. 675 - 688

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被引用次数: 15

摘要

The first substratelike, reversible inhibitors of different copper amine oxidases (CAOs) with IC50 (M) as low as 2.0× 10-8 corresponding to derivatives of 4-aminomethylpyridine with alkoxy (1a-d), alkylthio (2a, b), and alkylamino (3a-e, 4a-j) groups in the positions 3 and 5