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Med Chem Res

Ranjith Pakkath Karuvalam, Rajeesh Pakkath, Karickal Raman Haridas, Rathnasamy Rishikesan & Nalilu

S Kumari

文献索引:Karuvalam, Ranjith Pakkath; Pakkath, Rajeesh; Haridas, Karickal Raman; Rishikesan, Rathnasamy; Kumari, Nalilu Suchetha Medicinal Chemistry Research, 2013 , vol. 22, # 9 p. 4437 - 4454

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摘要

Abstract In this article, we report herein the SAR studies of a series of (1H-indol-3-yl) alkyl-3- (1H-indol-3-yl) propanamide 10 (a–j), 11 (a–j). The synthesized compounds were evaluated for their preliminary in vitro antibacterial, antifungal activity and were screened for antitubercular activity against Mycobacterium tuberculosis H37Rv strain. The synthesized compounds displayed interesting antimicrobial activity. Keywords Indole 4 Antibacterial ...