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Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

M Shindo, Y Yoshimura, M Hayashi, H Soejima…

文献索引:Shindo, Mitsuru; Yoshimura, Yutaka; Hayashi, Maiko; Soejima, Hiroe; Yoshikawa, Takashi; Matsumoto, Kenji; Shishido, Kozo Organic Letters, 2007 , vol. 9, # 10 p. 1963 - 1966

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被引用次数: 62

摘要

An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4+ 1] annulation by C2-C3 and C3-C4 bond formations includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.