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Diastereoselective Synthesis of C3??Quaternary Indolenines Using α, β??Unsaturated N??Aryl Ketonitrones and Activated Alkynes

CB Huehls, TS Hood, J Yang

文献索引:Huehls, C. Bryan; Hood, Tyler S.; Yang, Jiong Angewandte Chemie - International Edition, 2012 , vol. 51, # 21 p. 5110 - 5113

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被引用次数: 18

摘要

Indole-containing structures are ubiquitous in natural products, medicinal compounds, and organic materials.[1] Given their biomedical importance, synthetic methods towards these structural motifs remain relevant even after decades of innovations.[2] However, despite all the efforts toward the efficient construction of C3-quaternary indole derivatives, significant challenges remain.[3] These challenges are found in the forms of spirooxindole, ...