Chemistry Letters

Asymmetric transformation of amino acids in N-salicylidene amino acyl-L-isoleucinatocopper (II).

K Harada, K Shiono, S Nomoto

文献索引：Harada, Kaoru; Shiono, Katsuji; Nomoto, Shinya Chemistry Letters, 1980 , p. 1271 - 1274

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被引用次数: 3

摘要

A new asymmetric transformation of amino acids was described. Thus, when N-salicylidene- D-alanyl-, D-phenylalanyl-, or D-phenylglycyl-L-isoleucinatocopper (II) was incubated at pH 8.5 and 80° C, the resulting mixture at equilibrium contained a complex of LL-dipeptide in the contents of 63–76%. The epimerization of dipeptides is based on the enhanced activity of N-terminal amino acids through complex formation.