Synthesis and biological evaluation of 7-azaindole derivatives, synthetic cytokinin analogues

…, E Boissier, O Herault, MC Viaud-Massuard

文献索引：Guillard, Jerome; Decrop, Maylis; Gallay, Nathalie; Espanel, Claire; Boissier, Elodie; Herault, Olivier; Viaud-Massuard, Marie-Claude Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 7 p. 1934 - 1937

全文：HTML全文

被引用次数: 19

摘要

Cytokinins, N6-substituted adenine derivatives, are plant hormones playing important roles in various processes in plant development. Furthermore, cytokinins and their derivatives are able to control mammalian cell apoptosis and differentiation. The aim of our study was the synthesis of 7-azaindole derivatives as cytokinin analogues with the Hartwig–Buchwald coupling reaction in order to evaluate their biological properties on human myeloblastic ...