Synthesis and dihydropteridine reductase inhibitory effects of potential metabolites of the neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine

W Gessner, A Brossi, RS Shen…

文献索引：Gessner, Wieslaw; Brossi, Arnold; Shen, Rong-sen; Abell, Creed W. Journal of Medicinal Chemistry, 1985 , vol. 28, # 3 p. 311 - 317

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被引用次数: 34

摘要

Medicinal Chemistry Section, Laboratory of Chemistry, National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20205, and Department of Human Biological Chemistry and Genetics, Division of Biochemistry, The University of Texas Medical Branch, Galveston, Texas 77550. Received July 2, 1984 l-Methyl-4-phenyl-l, 2, 3, 6-tetrahydropyridine (MPTP) is a nigrostriatal ...