Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore

DJ Maly, F Leonetti, BJ Backes…

文献索引：Journal of Organic Chemistry, , vol. 67, # 3 p. 910 - 915

全文：HTML全文

被引用次数: 99

摘要

... The Journal of Organic ... J. Org. ... the use of the in situ activating agent HATU (N-[(dimethylamino)- 1-H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide) in the presence of an equimolar amount of the hindered organic base 2,4,6 ...