Synthesis and antifolate evaluation of 10-ethyl-5-methyl-5, 10-dideazaaminopterin and an alternative synthesis of 10-ethyl-10-deazaaminopterin (edatrexate)

JR Piper, CA Johnson, GM Otter…

文献索引：Journal of Medicinal Chemistry, , vol. 35, # 16 p. 3002 - 3006

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被引用次数: 23

摘要

... Cancer Chemother. Pharmacol. 1984,12, 26-30. (8 1992 American Chemical Society Page 2. Antifolate Actiuity of Dideazaaminopterins Scheme I Journal of Medicinal Chemistry, 1992, Vol. 35, No. 16 3008 CHZCH, c ! e C 0 2 CH 3 ...