Synthesis of LIAZAL TM, a retinoic acid metabolism blocking agent (ramba) with potential clinical applications in oncology and dermatology

…, A Raeymaekers, M Venet, G Sanz, W Wouters…

文献索引：Freyne; Raeymaekers; Venet; Sanz; Wouters; De Coster; Wauwe Bioorganic and medicinal chemistry letters, 1998 , vol. 8, # 3 p. 267 - 272

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被引用次数: 22

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis of LIAZAL TM (compound 9, R085246) is described. LIAZAL TM inhibits all-transretinoic acid metabolism and thereby exerts retinoid-like effects in vivo. ... The synthesis of LIAZAL tm (compound 9, R085246) is described. LIAZAL tm inhibits all-trans-retinoic acid ...