Small-molecule-based inhibition of histone demethylation in cells assessed by quantitative mass spectrometry

MM Mackeen, HB Kramer, KH Chang…

文献索引：Sugiyama, Toru; Kanai, Mitsuharu; Takenaka, Setsuko; Sugimori, Akira Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 4 p. 1331 - 1332

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被引用次数: 48

摘要

... Chemistry Research Laboratory and the Oxford Centre for Integrative Systems Biology ... approach is exemplified by the analysis of trimethylated lysine-9 levels in histone H3, following a simple chemical derivatization procedure ... Chemicals were from Sigma unless stated otherwise ...