Mass fragmentography of cortisol and cortisone: preliminary studies on the development of a reference method

HLJ Makin, DJH Trafford, NF Taylor

文献索引：Makin, Hugh L. J.; Trafford, David J. H.; Taylor, Norman F. Collection of Czechoslovak Chemical Communications, 2002 , vol. 67, # 1 p. 1 - 9

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被引用次数: 3

摘要

Abstract Cortisol and cortisone are the two main glucocorticoids found in human plasma. Cortisol is commonly measured as a means of assessing adrenal function, usually by immunoassay, but such procedures must be subject to proper quality control which ideally uses analyte target values measured by isotope dilution mass fragmentography (GC-MS). Three derivatives of these steroids have been investigated for their chromatographic and ...