5 thesis and for antimalarial testing. Compound 3 is like 1 except that 3 lacks the benzo group and the chlorines of 1. Compound 4 is a chain homologue of 2 and 3. The dihydrochloride of 3 is ineffective against P. berghei in mice and P. berghei in vitro (infra). We have been unable to synthesize 4. We did make the 9, lO-dihydro derivative of 4 which has negligible activity against P. berghei in mice. We have also made 5 which is ...
