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The Journal of Organic Chemistry

A simple conversion of 2-methoxynaphthoquinones to 2, 3, 4, 5-tetrahydronaphtho [1, 2-b] furan-4, 5-diones. Application to the synthesis of (.+-.)-trypethelones

V Guay, P Brassard

文献索引:Guay, Vincent; Brassard, Paul Journal of Organic Chemistry, 1984 , vol. 49, # 11 p. 1853 - 1857

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被引用次数: 7

摘要

Structures propcaed for trypethelone, 0-methyltrypethelone, and 0-methyl-8- methoxytrypethelone have been confirmed by synthesis. The required naphthoquinone substrates were prepared regiospecifically in one step by using vinylogous ketene acetals and then converted to the desired products essentially in a novel one-flask procedur 1

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