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Synthesis of Indoles through Highly Efficient Cascade Reactions of Sulfur Ylides and N??(ortho??Chloromethyl) aryl Amides

QQ Yang, C Xiao, LQ Lu, J An, F Tan…

文献索引:Yang, Qing-Qing; Xiao, Cong; Lu, Liang-Qiu; An, Jing; Tan, Fen; Li, Bin-Jie; Xiao, Wen-Jing Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9137 - 9140

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被引用次数: 23

摘要

As a consequence of its prevalence as a “privileged” structure in many natural isolates and therapeutic agents, the indole framework has continued to capture the interest of chemists worldwide.[1] Consequently, numerous efforts have been devoted to the development of efficient methods to construct the indole architecture.[2] Work on this problem dates back to the seminal studies by Fischer and Jourdan,[3] which led to the synthesis of indoles by ...