Synthesis of 2-amino-5, 7-dimethyl-4-oxopyrido [3, 4-e]-1, 3-thiazines

D Koščík, P Kristian, O Forgáč

文献索引：Koscik, Dusan; Kristian, Pavol; Forgac, Ondrej Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 12 p. 3426 - 3432

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被引用次数: 5

摘要

Abstract New synthesis of pyrido [3, 4-e]-1, 3-thiazines consisting in reaction of 2, 6-dimethyl- 4-chloronicotinoyl isothiocyanate with primary or secondary amines, or with benzaldehyde phenylhydrazone, is described. High reactivity of the chlorine atom does not allow isolation of the corresponding thioureas, arising as intermediates, except in the case of the benzylamino derivative. Structure of the products was unequivocally confirmed by their ...