Assessment of antiplatelet activity of 2-aminopyrimidines

…, RS Tamboli, R Ramajayam, DG Prajapati…

文献索引：Giridhar, Rajani; Tamboli, Riyaj S.; Ramajayam; Prajapati, Dhaval G.; Yadav European Journal of Medicinal Chemistry, 2012 , vol. 50, p. 428 - 432

全文：HTML全文

被引用次数: 10

摘要

A series of 4, 6-diaryl-2-aminopyrimidines was developed as antiplatelet agents and their potency was evaluated by in vitro assay. Compound 14k was found to be two times more potent than aspirin. These encouraging results could be helpful for the development of new antiplatelet compounds.