Tetrahedron letters

Additive effects on ligand activated allylation of aldehydes by allyltrichlorosilane

JD Short, S Attenoux, DJ Berrisford

文献索引：Short, Joanne D.; Attenoux, Sandrine; Berrisford, David J. Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2351 - 2354

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被引用次数: 50

摘要

The rate of allylation of aldehydes using a combination of allyltrichlorosilane and O-donor ligands can be profoundly accelerated by the addition of a range of simple tetra-n- butylammonium salts. Measured t1 2 values decrease from over 6 hours under defined conditions to less than 5 minutes in favourable cases. These effects are highly relevant to the development of a catalytic asymmetric variant of this reaction and provide insight into ...