Journal of heterocyclic chemistry

1, 3??cycloaddition of substituted benzonitrile oxides to aliphatic nitriles. The kinetic effect of substituents

P Beltrame, G Gelli, A Loi

文献索引：Beltrame, Paolo; Gelli, Gioanna; Loi, Aldo Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1609 - 1612

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被引用次数: 5

摘要

Abstract A previous study of the reaction of aromatic nitrile oxides with simple aliphatic nitriles, with the formation of 3, 5-disubstituted 1, 2, 4-oxadiazoles, has been extended to a larger number of nitrile oxides. Sixteen new oxadiazole derivatives have been prepared and characterized. Cycloaddition rates have been measured in the temperature range from 50 to 80. When considering the effect of substituents on the aromatic ring, roughly V-shaped ...