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Design and synthesis of reboxetine analogs morpholine derivatives as selective norepinephrine reuptake inhibitors

W Xu, DL Gray, SA Glase, NS Barta

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 20 p. 5550 - 5553

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被引用次数: 22

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 1). A number of such compounds were synthesized using the described chemistry and several of these morpholine derivatives are potent and selective NRI's as demonstrated by the measured MAT binding affinities for representative ...