Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR)

B Flatt, R Martin, TL Wang, P Mahaney…

文献索引：Journal of Medicinal Chemistry, , vol. 52, # 4 p. 904 - 907

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被引用次数: 92

摘要

... Journal of ... J. Med. Chem. , 2009, 52 (4), pp 904–907. DOI: 10.1021/jm8014124. Publication Date (Web): January 21, 2009. Copyright © 2009 American Chemical Society. * To whom correspondence should be addressed. ... Department of Medicinal Chemistry, Exelixis Inc. , § ...