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Synthetic Communications

Bromination of arenes using I2O5-KBr in water

J Hou, Z Li, XD Jia, ZQ Liu

文献索引:Hou, Jieping; Li, Zejiang; Jia, Xiao-Dong; Liu, Zhong-Quan Synthetic Communications, 2014 , vol. 44, # 2 p. 181 - 187

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被引用次数: 7

摘要

An efficient and environmentally benign bromination of various aromatic compounds using aN aqueous I 2 O 5 -KBr system at room temperature has been developed in this work. A series of aromatic compounds such as acetophenones, benzaldehydes, benzoic acids, anilines, amides, and aminopyridine have been successfully brominated in excellent regioselectivities and good yields under the typical reaction conditions. The features of KBr as brominating ...