Synthesis of cystamine

…, TE Kuznetsova, SV Nekrasov, BV Passet

文献索引：Bulat, a. D.; Grishin, V. V.; Kuznetsova, T. E.; Nekrasov, S. V.; Passet, B. V. Pharmaceutical Chemistry Journal, 1990 , vol. 24, # 5 p. 376 - 378 Khimiko-Farmatsevticheskii Zhurnal, 1990 , vol. 24, # 5 p. 57 - 59

全文：HTML全文

被引用次数: 0

摘要

Several methods are given in the literature for the preparation of cystamine (I)[bis (~- aminoethyl) disulfide dihydrochloride], starting from~-chloroethylamine hydrochloride (II). By the first method, the starting compound is treated in an aqueous alkaline solution with carbon disulfide, the 2-mercaptothiazoline obtained is hydrolyzed in an acid medium to the key intermediate-~-mercaptoethylamine (III)[3]-which is then oxidized into I by various ...