One-pot one-step deracemization of amines using ω-transaminases

G Shin, S Mathew, M Shon, BG Kim…

文献索引：Shin, Giyoung; Mathew, Sam; Shon, Minsu; Kim, Byung-Gee; Yun, Hyungdon Chemical Communications, 2013 , vol. 49, # 77 p. 8629 - 8631

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被引用次数: 23

摘要

In this study, we developed a one-pot one-step deracemization method for the production of various enantiomerically pure amines using two opposite enantioselective ω-TAs. Using this method, various aromatic amines were successfully converted to their (R)-forms (> 99%) with good conversion.