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A study of chemical carcinogenesis. 57. Synthesis and mutagenicity of dihydrodiol metabolites of benzo [b] fluoranthene

S Amin, N Hussain, H Brielmann…

文献索引:Amin, Shantu; Hussain, Nalband; Brielmann, Harry; Hecht, Stephen S. Journal of Organic Chemistry, 1984 , vol. 49, # 6 p. 1091 - 1095

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被引用次数: 12

摘要

(14) Harvey, RG; Fu, PP In" Polycyclic Hydrocarbons and Cancer"; Gelboin, HV, T'so, P. 0. P., Eds.; Academic Press: New York, 1978; Vol 1, pp 133-165. of 17. Coupling, hydroboration, and a two-step oxidation procedure gave the desired butyric acid derivative 21. Cyclization of the acid chloride of 21 proceeded specifically to ketone 22, the structure of which was established by the presence in its NMR spectrum of the downfield Hl proton ...

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