Highly efficient and mild copper??catalyzed N??and C??arylations with aryl bromides and iodides

…, PP Cellier, JF Spindler, M Taillefer

文献索引：Cristau, Henri-Jean; Cellier, Pascal P.; Spindler, Jean-Francis; Taillefer, Marc Chemistry - A European Journal, 2004 , vol. 10, # 22 p. 5607 - 5622

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被引用次数: 522

摘要

Abstract Mild, efficient, copper-catalyzed N-arylation procedures for nitrogen heterocycles, amides, carbamates, and C-arylation procedures for malonic acid derivatives have been developed that afford high yields of arylated products with excellent selectivity. The N- arylation of imidazole with aryl bromides or iodides was found to be greatly accelerated by inexpensive, air-stable catalyst systems, combining catalytic copper salts or oxides with a ...