N-arylsulfonyl hydrazones as inhibitors of IMP-1 metallo-β-lactamase

S Siemann, DP Evanoff, L Marrone…

文献索引：Antimicrobial Agents and Chemotherapy, , vol. 46, # 8 p. 2450 - 2457

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被引用次数: 90

摘要

... In a typical assay (final volume, 1 ml), metallo-β-lactamase (4 nM) in HEPES buffer ... with the enzyme, with the final concentration of DMSO in the assay not exceeding 1% (vol/vol). ... 1), and (ii) their potential to function as moderate binding agents for divalent metal ions, provided ...