Tetrahedron Letters

The efficient one-step chlorination of methylsulfanyl group on pyrimidine ring system with sulfuryl chloride

YJ Ham, DH Lee, HG Choi, JM Hah, T Sim

文献索引：Ham, Young Jin; Lee, Duck-Hyung; Choi, Hwan Geun; Hah, Jung-Mi; Sim, Taebo Tetrahedron Letters, 2010 , vol. 51, # 35 p. 4609 - 4611

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被引用次数: 1

摘要

Taking into account that heteroaromatic rings have widely been adopted as one of the most privileged core structures of drugs in the market, their efficient chemical transformations have received a great deal of attention in the field of organic and medicinal chemistry. 1 In particular, extensive efforts have been devoted to handle effectively pyrimidine and purine analogs in the area of medicinal chemistry. 2 An alkylsulfanyl group such as methylsulfanyl group, widely been ...