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Lewis acid catalyzed Nenitzescu indole synthesis

VS Velezheva, AG Kornienko, SV Topilin…

文献索引:Velezheva, Valeriya S.; Kornienko, Albert G.; Topilin, Sergey V.; Turashev, Ascar D.; Peregudov, Alexander S.; Brennan, Patrick J. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 873 - 879

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被引用次数: 18

摘要

5-Hydroxyindoles are found in nature and display a wide variety of biological activities [1, 2]. A series of polysubstituted 5-hydroxyindole-based agents have been developed recently including the antiviral and immunomodulatory drug arbidol, ethyl 6-bromo-4- dimethylaminomethyl-5-hydroxy-1-methyl-2-phenylthio-methylindole-3-carboxylate hydrochloride [3](and its 4-substituted derivatives [4]), as well as compounds of potential ...