Imine-Directed metalation of o-tolualdehyde: the use of catalytic amine base. A route to 2-(8-phenyloctyl) benzaldehyde

MA Forth, MB Mitchell, SAC Smith…

文献索引：Journal of Organic Chemistry, , vol. 59, # 9 p. 2616 - 2619

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被引用次数: 13

摘要

... 2Is2 The first synthesis of 2 proceeded from 2-(8-phenyloctyl)benzaldehyde (1) via Darzen's chemistry, nonregioselective epoxide ... ammonium chloride solution (170 L) and a 20 % sodium chloride solution (3 X 197 L). The organic solution was ... (20) Collins, RF; Davie, M. J. Chem ...