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Helvetica chimica acta

Optical Resolution of (RS)??Pantolactone through Amide Formation

C Fizet

文献索引:Fizet, Christian Helvetica Chimica Acta, 1986 , vol. 69, p. 404 - 409

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被引用次数: 7

摘要

Abstract The optical resolution of (RS)-pantolactone (1) is carried out through formation of diastereoisomeric amides. These are separated by a single hot washing with CH 2 C1 2 or CHC1 3. The used asymmetric amine,(1R)-3-endo-aminoborneol (4), is readily accessible