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Synthesis and Evaluation of Antimicrobial Activity of Some New Hetaryl??Azoles Derivatives Obtained from 2??Aryl??4??methylthiazol??5??carbohydrazides and Isonicotinic …

…, V Zaharia, I Colosi, C Moldovan…

文献索引:Tiperciuc, Brindusa; Zaharia, Valentin; Colosi, Ioana; Moldovan, Cristina; Crisan, Ovidiu; Pirnau, Adrian; Vlase, Laurian; Duma, Mihaela; Oniga, Ovidiu Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 6 p. 1407 - 1414

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被引用次数: 9

摘要

Abstract A series of new 1, 3, 4-oxadiazole/thiadiazole and 1, 2, 4-triazole derivatives have been synthesized starting from 2-aryl-4-methylthiazol-5-carbohydrazides and isonicotinic acid hydrazide. All the newly synthesized compounds were characterized by IR, 1 H NMR, 13 C NMR, and mass spectrometry. The synthesized compounds were screened for their antibacterial and antifungal activity, assessed as growth inhibition diameter. Some of them ...