Amino acids

Synthesis of potentially bioactive PABA-related N-(aminoalkyl) lactamic amino acids and esters via selective SNAr reactions

RS Gonçalves, PV Abdelnur, VG Santos, RC Simas…

文献索引：Amino Acids, , vol. 40, # 1 p. 197 - 204

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被引用次数: 6

摘要

... synthesized in satisfactory to good yields by S N Ar reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. ... Derivatives of p-aminobenzoic acid (PABA) have shown interesting pharmacological properties (Kabbani et ...