The Journal of organic chemistry

Preparation of Trifluorostyrenes via Palladium-Catalyzed Coupling of Arylboronic Acids with Chloro-and Bromotrifluoroethylene

C Xu, S Chen, L Lu, Q Shen

文献索引：Xu, Chunfa; Chen, Sheng; Lu, Long; Shen, Qilong Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10314 - 10320

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被引用次数: 8

摘要

A highly efficient and cost-effective method for the preparation of α, β, β-trifluorostyrene (TFS) and its derivatives is described. The method required only 0.2 mol% of Pd (dba) 2 and 0.4 mol% of P t Bu3 and occurred to full conversion within 2.0 h. With this method, a wide range of arylboronic acids were efficiently incorporated to generate α, β, β-trifluorostyrene derivatives.