The Journal of Organic Chemistry

A new method for the synthesis of heptamethine cyanine dyes: synthesis of new near-infrared fluorescent labels

N Narayanan, G Patonay

文献索引：Narayanan, Narasimhachari; Patonay, Gabor Journal of Organic Chemistry, 1995 , vol. 60, # 8 p. 2391 - 2395

全文：HTML全文

被引用次数: 177

摘要

2, 3, 34rimethylbenzindole and 2-chloro-l-formyl-3-(hydroxymethylene) cyclohex-l-ene to reflux in a mixture of 1-butanol and benzene (7: 3) as solvent. No catalyst is used, and water is removed as an azeotrope. The resulting chloro compounds possess strong absorption and fluorescence properties in the near-infrared region and are converted to dyes bearing reactive functionalities such as hydroxy and isothiocyanate groups useful as fluorescent ...