Summary The possibility of orthor nuclear oxidation in the flavone series has been tested using 7-hydroxy-flavone and 3-methoxy-7-hydroxyl-flavone. By means of alkaline persulphate 7: 8-dihydroxy-flavone (10% yield) and 3-methoxy-7: 8-dihydroxy-flavone (20% yield) could be obtained. This seems to offer an easier method of preparing the flavonol, 3: 7: 8-trihydroxy flavone. The intermediate stage of the sulphate could be isolated pure from ...
[Dhawan, Deepika; Grover, S. K. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1997 , vol. 36, # 1 p. 73 - 74]