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Synthesis of aza macrocycles by nucleophilic ring closure with cesium tosylamides

BK Vriesema, J Buter, RM Kellogg

文献索引:Vriesema, Bindert K.; Buter, Jan; Kellogg, Richard M. Journal of Organic Chemistry, 1984 , vol. 49, # 1 p. 110 - 113

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被引用次数: 96

摘要

Results We have examined the general synthetic scheme shown in eq 2, which is analogous in character to routes followed by Stetter4 and Richmanas The reaction of 12- ,[Cs+] z and 2 to form 3 is assumed to involve a sequence of two nu-(6)(a) Badawi, MM; Bernauer, K.; van den Broek, P.; Groger, G.; Guggisberg, A,; Johne, S.; Kompis, L.; Schneider, F.; Veith, H.-J.; Hesse, M.; Schmid, H.; Pure Appl. Chem. 1973, 33, 81.(b)" ...