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Organic letters

Electrosynthesis of Substituted 1 H-Indoles from o-Nitrostyrenes

P Du, JL Brosmer, DG Peters

文献索引:Du, Peng; Brosmer, Jonathan L.; Peters, Dennis G. Organic Letters, 2011 , vol. 13, # 15 p. 4072 - 4075

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被引用次数: 6

摘要

A novel procedure has been devised for the synthesis of derivatives of 1 H-indole that is based on the direct, room-temperature electrochemical reduction of substituted o- nitrostyrenes at carbon cathodes in N, N-dimethylformamide containing tetramethylammonium tetrafluoroborate as supporting electrolyte and in the presence of a 10-fold molar excess of a proton donor (phenol or methyl 3-oxobutanoate).