A sequential enantioselective, organocatalytic route to chiral 1, 2-oxazines and chiral pyridazines

…, AJ Oelke, DM Shaw, DA Longbottom…

文献索引：Kumarn, Sirirat; Oelke, Alexander J.; Shaw, David M.; Longbottom, Deborah A.; Ley, Steven V. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2678 - 2689

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被引用次数: 34

摘要

The synthetic potential of multicomponent, tandem or domino reactions has been exploited for the efficient and stereoselective construction of a variety of complex structures from simple starting materials. 1 These one-pot sequential transformations avoid lengthy purification or protection procedures and thus greatly reduce both the cost and time taken for chemical syntheses. In recent years, spectacular advances have been made in organocatalytic processes 2 and one ...