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Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives

PL Beaulieu, M Bös, Y Bousquet, G Fazal…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 119 - 124

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被引用次数: 113

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 4 A significant proportion of the patient population does not respond to therapy and there is an urgent demand for novel strategies addressing this clearly unmet medical need. 5a. ...