Abstract A series of 1, 4-bis (4-guanylphenylethyl) benzenes, including masked amidines in which the guanyl function is incorporated into a heterocyclic ring, were prepared for screening as potential antitrypano-somal agents. Some of these compounds were active against Trypano-soma rhodesiense in mice. The diamidines were prepared by standard methods from 1, 4-bis (4-cyanophenylethyl) benzene which was obtained from 1, 4-bis (4- ...
[Lokhande, S. B.; Rangnekar, D. W. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 485 - 488]
