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Indium-mediated allylation of acyl cyanides in aqueous media: A convenient synthesis of β, γ-unsaturated ketones

…, KH Choi, SJ Lee, GS Nam, KY Chang…

文献索引:Yoo, Byung Woo; Choi, Kwang Hyun; Lee, Sung Jae; Nam, Ghil Soo; Chang, Kwan Young; Kim, Sung Hoon; Kim, Joong Hyup Synthetic Communications, 2002 , vol. 32, # 6 p. 839 - 846

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被引用次数: 10

摘要

View all references However, these reactions are of limited application, not being very simple and straightforward. We have found that acyl cyanide can act as an electrophile in the indium-mediated allylation in aqueous media to achieve carbon–carbon bond formation. To the best of our knowledge, the indium-mediated allylation has never been applied to acyl cyanides as activated carboxylic acid derivative. In our methodology synthesizing β,γ-unsaturated ...