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The Journal of organic chemistry

Propargyl bromide as an excellent α-bromoacetone equivalent: Convenient and new route to α-aroylacetones

SM Mahalingam, IS Aidhen

文献索引:Vijayasaradhi; Aidhen, Indrapal Singh Organic Letters, 2002 ,  vol. 4,  # 10  p. 1739 - 1742

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被引用次数: 12

摘要

A variety of α-aroylacetones 4a-g have been prepared in excellent yields following a new protocol wherein α-aminonitriles 1a-g as the aryl acyl anion equivalents readily react with propargyl bromide as the α-bromoacetone equivalent. The alkylated product undergoes one-